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Ionic Current through Membrane Conductance

Ionic Current through Membrane Conductance
\[I=g(V_m-E_{ion})\]

Variables

Iionic current (A)
gmembrane conductance (S)
Vmmembrane potential (V)
Eionequilibrium potential of the ion (V)

Description

What is this formula?

This formula calculates the ionic current flowing through a membrane channel based on membrane conductance and the electrochemical driving force.


When to use it

Use this formula in electrophysiology and membrane biophysics when analyzing ion channel currents and membrane electrical behavior.


Example

A membrane channel has:

g=2.0×10^-9 S

Vm=-0.050 V

Eion=-0.080 V


Formula:

I=g*(Vm-Eion)


Substitution:

I=(2.0×10^-9)*((-0.050)-(-0.080))


Result:

I=6.0×10^-11 A


The ionic current is 60 pA.


Applications

- Ion channel analysis

- Neuron electrophysiology

- Cardiac membrane studies

- Bioelectric modeling

- Cellular signaling research

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